Non-invasive pre-natal testing

The Harmony Prenatal Test

This analyses cell free DNA in a pregnant mothers blood. It is a new option for Downs Syndrome (Trisomy 21) and other common fetal chromosomal conditions such as, Trisomy 18 (Edwards Syndrome) and Trisomy 13 (Patau Syndrome) and exceeds the accuracy of the 12 week nuchal scan in detecting these abnormalities.


The testing is non-invasive. It involves taking a blood sample from the mother. The pregnancy is not put at risk of miscarriage  or other adverse outcomes with invasive testing procedures such as CVS or amniocentesis.


The test identifies more than 99% of fetuses with Trisomy 21, 97% of fetuses with Trisomy 18 and 80% of fetuses with Trisomy 13.  A high risk result suggests a high risk for a Trisomy but does not mean definitely that it has one of the above conditions, although it is highly likely and it is recommended that an invasive procedure be performed to confirm whether this is the case.

Who can have the test?

The test may be carried out from 10 weeks of pregnancy. An ultrasound scan is needed to confirm and date the pregnancy by size and confirm a singleton pregnancy. In addition it can be requested for IVF singleton pregnancies including donor and surrogate pregnancies. It cannot be performed in cases of multiple pregnancy.

How long does it take to get the results?

The results are available in 2 weeks

Do I need any other tests?

The Harmony Test does not provide information on other physical defects, such as spina bifida or fetal heart abnormalities and growth. It is advisable therefore to have a 12 week scan for a detailed examination of your baby.