Mr William Dennes PhD, MRCOG
Mr Dennes is a Consultant Obstetrician and Sub-specialist in Maternal and Fetal Medicine. He is a Consultant at King’s College Hospital, London. He works both in the NHS and Privately, looking after mothers at both King’s College Hospital (the Guthrie Wing) and the Portland Hospital.Mr Dennes is experienced in the management of women in pregnancy, and has a special interest in multiple pregnancies and high-risk obstetric cases. He is accredited as a sub-specialist in fetal and maternal medicine, and is experienced in all aspects of antenatal ultrasound imaging (both conventional and 3D/4D).
Mr Dennes is accredited with the Fetal Medicine Foundation and routinely carries out invasive prenatal diagnostic testing (amniocentesis and chorionic villous sampling).
Qualifications:
MB BS – Royal Free Hospital School of Medicine (University of London)
MRCOG – Membership of the Royal College of Obstetricians and Gynaecologists, London
PhD – Imperial College, London
Mr Dennes graduated in London and subsequently went on to specialised training in obstetrics and gynaecology in London and the North West Thames region. Initially training at the Hammersmith Hospital (under Prof Winston) he returned to Hammersmith and Queen Charlotte’s Hospitals for further postgraduate research, completing his PhD thesis on the Molecular mechanisms involved in preterm labour, with Prof Phillip Bennett. Following completion of training in obstetrics and Gynaecology he underwent sub-speciality training in Maternal and Fetal Medicine, at the Centre for Fetal, Care at Queen Charlotte’s and Chelsea Hospital (under Prof Nicholas Fisk) a nationally recognised fetal medicine centre. He completed sub-specialty training in maternal and fetal medicine in 2005. He was appointed as a Consultant Obstetrician at King’s College Hospital in London, with a specialist interest in fetal medicine, where he works in the Harris Birthright Centre for Research, with Prof Kypros Nicolaides.
Mr Dennes has contributed to publications in the field of obstetrics and fetal medicine, and reviews papers for peer-reviewed journals. He has contributed chapters to: ‘Proceedings of the Royal College of Obstetricians and Gynaecologists’, ‘Fetal Medicine’, ‘The Unborn patient: the art and science of fetal therapy’, ‘Progress in Obstetrics and Gynaecology, and the ‘Royal College of Obstetricians and Gynaecologists Yearbook’. He is a member of the British Association of Perinatal Medicine, and the British Maternal Fetal Medicine Society.
| Mr. William Dennes, PhD MRCOG |
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| Practice Address: | 92 Harley Street London W1G 7HU Fax: 020 7034 1301 Tel: 020 7034 1300 |
| Nationality: | British |
| CCST date: | 5 October 2005 |
| GMC Registration: | 3405804 Specialist Registration: Obstetrics and Gynaecology Sub speciality: Maternal and Fetal Medicine |
| Medical Education: | Royal Free Hospital School of Medicine (University of London), 1984 – 1989 |
| Qualifications: | MB BS (London) – 1989 PhD (Imperial College, London) – 2001 MRCOG – 2002 |
| Present Appointments: | Consultant in Obstetrics and Fetal Medicine King’s College Hospital Denmark Hill London SE5 9RS Tel: 020 7737 4000 x 4326 Fax: 020 7346 3445 E-mail: william.dennes@kingsch.nhs.uk Consultant in Obstetrics and Fetal Medicine Honorary Consultant in Obstetrics and Fetal Medicine |
| Previous Appointments: | |
| August 2003 – January 2006 | Sub-specialty trainee Maternal Fetal Medicine Centre for Fetal Care Queen Charlotte’s and Chelsea Hospital, London |
| March 2003 – July 2003 | Specialist Registrar in Obstetrics and Gynaecology (Year 5) Queen Charlotte’s and Chelsea Hospital, London |
| March 2002 – February 2003 | Specialist Registrar in Obstetrics and Gynaecology (Year 4) Watford General Hospital, Watford, Hertfordshire |
| March 2001 – February 2002 | Specialist Registrar in Obstetrics and Gynaecology (Year 3) Queen Elizabeth II Hospital, Welwyn Garden City Hertfordshire |
| March 2000 – February 2001 | Specialist Registrar in Obstetrics and Gynaecology (Year 2) Chelsea and Westminster Hospital, London |
| March 1999 – February 2000 | Specialist Registrar in Obstetrics and Gynaecology (Year 1) Northwick Park Hospital, Middlesex |
| February 1996 – February 1999 | Research Fellow (Honorary Registrar). Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical School, Queen Charlotte’s and Chelsea Hospital, London |
| August 1995 – January 1996 | Senior House Officer in Gynaecology, Hammersmith Hospital, London |
| February 1995 – July 1995 | Senior House Officer in Obstetrics, Hammersmith Hospital, London |
| August 1994 – January 1995 | Senior House Officer in Obstetrics and Gynaecology, Louise Margaret Maternity Wing, Cambridge Military Hospital, Aldershot |
| August 1990 – January 1991 | Senior House Officer in Accident and Emergency, Accident and Emergency Department, Guy’s Hospital, London |
| Committees: | Clinical Consent Committee, Chelsea and Westminster Hospital (2000 – 2001)
Obstetric Lead – Cord Blood Banking Committee, King’s College London (in collaboration with the Antony Nolan Cord Blood Bank) |
| Obstetric Lead – Cord Blood Banking Committee, King’s College London (in collaboration with the Antony Nolan Cord Blood Bank) | |
| Council Member – Gerson Lehrman Group | |
| Medico-legal Work: | Preparation of Expert witness reports. |
| Teaching: | Course Lecturer, OSCE Examiner MBBS King’s College Hospital, London |
| Course Lecturer, Examiner and administrator: MSc in Obstetric Ultrasound MSc in Reproductive Biology BSc in Paediatrics Institute of Obstetrics and Gynaecology, Imperial College School of Medicine, Queen Charlotte’s and Chelsea Hospital, London (2003 – 2005) |
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| Multiple Birth Foundation – National Screening Committee Study Day Hammersmith Hospital London. ‘The clinical perspective – what is possible?’ |
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| Legal and Ethical Issues in Reproductive Medicine Institute of Reproductive and Developmental Biology Imperial College London. ‘Obstetric outcome of assisted reproductive techniques’ |
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| Publications: | |
| Papers: | H Gardiner, C Belmar, L Pasquini, A Seale, M Thomas, W Dennes, M Taylor, E Kulinskaya, R Wimalasundera. Fetal ECG: A Novel Predictor of Atrioventricular Block in Anti-Ro Positive Pregnancies. Heart. 2006. |
| Elliott C L, Slater D M, Dennes W J B, Poston L, Bennett P R. Interleukin 8 expression in human myometrium: changes in relation to labour onset and with gestational age. Am J Reprod Immunol: 43: 5, 272-7, 2000 | |
| Sawdy R J, Slater D M, Dennes W J B, Sullivan M. H, Bennett P R: The roles of the cyclo-oxygenases types one and two in prostaglandin synthesis in human fetal membranes at term. Placenta : 21: 1, 54-57, 2000 | |
| Bartlett S. R, Bennett P. R, Campa J. S, Dennes W J B, Slater D. M, Mann G. E, Poston L. Poston, R: Expression of nitric oxide synthase isoforms in pregnant human myometrium. J Physiol (Lond): 521 (Part 3), 705-716, 1999 | |
| Dennes W J B, Slater D M, Poston L, Bennett P R: Myometrial Nitric Oxide Synthase mRNA expression does not change throughout gestation, or with the onset of labour. Am J Obstet Gynecol. 180: 2, 387-392, 1999 | |
| Slater D M, Dennes W J B, Campa S J, Poston L, Bennett P R: Expression of cyclo-oxygenase types-1 and -2 in human myometrium throughout pregnancy. Mol Hum Reprod: 5: 1, 880-884, 1999 | |
| Sawdy R J, Dennes W J B, Allport V, Slater D M, Elder M G, Sullivan M H, Bennett P R: Region and labour-dependent synthesis of prostaglandin E2 by human fetal membranes. Placenta: 20 (2-3): 181-184, 1999 | |
| Slater D M, Dennes W J B, Sawdy R J, Allport V, Bennett P R: Expression of cyclo-oxygenase types-1 and -2 in human fetal membranes throughout pregnancy: J Mol Endocrinol: 22 (2): 125-130, 1999 | |
| Dennes W J B, Slater D M and Bennett P R: Nitric oxide synthase mRNA expression in human fetal membranes: A possible role in parturition. Biochem Biophys Res Comm. 233: 276-278, 1997 | |
| Dennes W J B, Slater D M and Bennett P R: Nitric Oxide and the control of human parturition. Con Rev Obs Gynae 9: 245-251, 1997 | |
| Dennes W J B, Slater DM and Bennett PR: Differential expression of Nitric oxide synthase mRNA in fetal membranes, before and after the onset of labour. Br J Obstet Gynaecol. 104: 633, 1997 | |
| Book Chapters: | Dennes W J B and Fisk N M. ‘Scientific basis of twin-twin transfusion syndrome’. In: Multiple Pregnancy, Ed M. Kilby. Proceedings of the Royal College of Obstetricians and Gynaecologists Study Group. London: RCOG. 2006. |
| Lewi L, Dennes W J B, Fisk N M and Deprest J. ‘Twin Twin Transfusion Syndrome – Prenatal Therapy’. In: Fetal Medicine, Eds M. G. van Vugt, L. Shulman. New York: Marcel Dekker. 2005. | |
| Dennes W J B and Bennett P R. ‘Preterm labour – the Achilles’ heel of fetal intervention’. In: The Unborn Patient: The Art and Science of Fetal Therapy. Eds M Harrison, M Evans, S Adzick, W Holzgreve. Philadelphia: W.B. Saunders. 2000 | |
| Dennes W J B, Sawdy R J and Bennett P R, ‘Molecular Biology in Obstetrics’. In: Progress in Obstetrics and Gynaecology – 13. Ed J. Studd. Edinburgh: Churchill Livingstone. 1999 | |
| Dennes W J B, Elliot C L and Bennett P R, ‘Mechanisms of Preterm labour’. In: 1998 Royal College of Obstetricians and Gynaecologists Yearbook. London: RCOG. 1999 | |
| Published Abstracts: | Bartlett S, Sawdy R, Dennes W J B, Bennett P R, Mann G E, Poston L. Cytokine regulation of nitric oxide synthase and cyclo-oxygenase-2 in cultured human myometrial cells. Society for Gynecologic Investigation, Atlanta, USA, February 1998. In Suppl. J Soc Gynecol Inv. 5: Abstract #F589. 1998 |
| Dennes W J B, Slater D M, Jones G D, Poston L and Bennett P R. Nitric oxide synthase expression in human myometrium, before and after the onset of labour. International Congress on Nitric oxide in reproductive and perinatal medicine, Genoa, Italy, September 1997. In Prenat Neonat Med: 2, 9, 1997 | |
| Slater D M, Dennes W J B, Sawdy R, Davies V and Bennett P R. Cyclo-oxygenase type 2 selective NSAI’s for inhibition of preterm labour. 4th International Congress on Essential Fatty Acids. Edinburgh, July 1997. In Prostagland Leuko Essent: 57: (Abstract M11) 1997 | |
| Dennes W J B, Slater D M and Bennett P R. Nitric oxide synthase mRNA expression in fetal membranes before and after labour. Society for Gynecologic Investigation, San Diego, USA, March 1997. In Suppl. J Soc Gynecol Inv. 4: Abstract #738. 1997 | |
| Slater D M, Dennes W J B, Jones G D, Poston L and Bennett P R. Expression of COX-1 and COX-2 in human myometrium: Changes in relation to gestational age and labour onset. Society for Gynecologic Investigation, San Diego, USA, March 1997. In Suppl. J Soc Gynecol Inv. 4: Abstract #146.1997 | |
| Oral Communications: | Dennes W J B, Pasquini L, Fisk N M, Gardiner H M. A comparison of conventional 2D fetal echocardiography and 3D Spatio-Temporal Image Correlation (STIC). International Fetal Medicine Surgery Society Meeting, Helsingor, Denmark. May 2005 |
| Dennes W J B, Slater D M, and Bennett P R: Expression and localisation of Nitric oxide synthase mRNA in human fetal membranes. Victor Bonney Society Meeting, Nuthurst Priory, May 1997 | |
| Dennes W J B, Slater D M, Jones G D, Poston L and Bennett P R. Nitric oxide synthase mRNA expression in human myometrium throughout gestation, and before and after the onset of labour. Blair Bell Jubilee Competition, RCOG London. December 1997 | |
| Poster Presentations: | Dennes W J B, O’Brien A, Vanderheyden T, Wimalasundera R, Fisk N M, Rutherford M A, Kumar S. Dandy-Walker variant malformations – correlation of MR imaging with detailed ultrasound examination. British Maternal and Fetal Medicine Society meeting, Glasgow. April 2004 | Societies: |
| Fellow of the Royal Society of Medicine. Member of the Blair Bell Research Society Member of The British Association of Perinatal Medicine Member of The British Maternal and Fetal Medicine Society |
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